CHO Cell Line Characterization Services
Unlock the Power of AI-Driven Morphology for CHO Cell Line Development
Deepcell Express now offers comprehensive CHO cell characterization, powered by Deepcell’s proprietary REM-i platform. REM-i, AI-driven imaging and analysis platform captures the rich morphological signatures of living cells, label-free.
Our service combines traditional analytical QC with next-generation morphology profiling, giving you a multidimensional view of cell identity, health, and productivity that accelerates clone selection, process optimization, and comparability studies.
Why REM-i for CHO Cell Characterization?
Traditional CHO testing reveals what is present, REM-i reveals how your cells behave.
REM-i uses high-resolution brightfield imaging and proprietary AI models to quantify subtle phenotypic features linked to:
Cellular productivity and metabolic state
Stress and granularity patterns
Viability, health, and subpopulation heterogeneity
Early predictive markers of clone performance
By integrating REM-i into the CHO characterization workflow, you gain a richer understanding of your cell banks — beyond what molecular or biochemical assays alone can provide.
AI-Driven Productivity Prediction
Why this matters
Picking winners early saves months of culture time and thousands of dollars per clone. Traditional screening leans on secreted titer assays that are slow and destructive and often miss subtle phenotypes tied to long-term stability. In contrast, REM-i uses label-free brightfield imaging with AI to quantify morphology at scale, revealing patterns linked to cell-specific productivity (Qp), viability trajectories, and clonal stability. Evidence across the literature shows that cell morphology carries productivity signal, from classic CHO clone selection by morphology to modern label-free imaging + ML approaches.
REM-i morphology profiling predict productivity differences
Low producing CHO cells
High producing CHO cells
What’s differentiated
Label-free & fast: No staining. Thousands of cells analyzed in minutes.
Single-cell resolution: Detect rare sub-populations that depress lot-level yield or stability. Single-cell studies consistently show hidden clonal heterogeneity in CHO lines.
Actionable early: Use morphology-based predictions before bulk titer diverges to prioritize clones and reduce wet-lab screening load.
Cell Characterization Services
Essential ID & Health Panel
$4,900 per bank | Turnaround: ~10 business days
Cell identity (STR profiling)
Viability and morphology inspection (basic REM-i morphology profile included)
Mycoplasma PCR screen
Sterility culture (bacterial & fungal)
Endotoxin test (recombinant Factor C)
Digital certificate of analysis + image gallery
Ideal for: Early clone screening or cell-line authentication.
Enhanced Analytical Panel
$12,900 per bank | Turnaround: ~3 weeks
Includes Tier 1, plus:
Residual host-cell DNA qPCR quantification
Host-cell protein (HCP) ELISA profile
Mycoplasma culture confirmation
Extended REM-i morphology profiling with AI-derived metrics:
Cell size & shape distributions
Stress & granularity indices
Population heterogeneity heatmap
Ideal for: Process-development teams optimizing stable clones or bioproduction conditions.
Pre-GMP Readiness Panel
$29,900 per bank | Turnaround: ~4–5 weeks
Includes Tier 2, plus:
In-vitro adventitious virus PCR screen (ICH Q5A R2-aligned)
TEM imaging for retrovirus-like particles
Stability check (0 and 3-month pulls for viability + REM-i profile)
Comprehensive digital report summarizing identity, purity, viability, and morphological fidelity
Ideal for: Pre-GMP comparability, tech-transfer, and regulatory-ready analytical packages.